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INTRODUCTION:

The central dogma of molecular biology was first articulated by Francis Crick in 1958 and re-stated in a Nature paper published in 1970: “The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that information cannot be transferred back from protein to either protein or nucleic acid.” The dogma is a framework for understanding the transfer of sequence information between sequential information-carrying biopolymers, in ....etc

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Abstract

Here, students learn that the comparison of DNA sequences is important to a wide variety of applications in medicine and biology, including the analyses of ecosystem biodiversity, cancer mutations and the evolution of viruses. The students learn that specialized yet inexpensive digital hardware based on field programmable gate arrays can help speed the analysis of DNA sequences. They design and test a simple implementation of the Smith-Waterman algorithm that is broadly used for DNA sequence c ....etc

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